ReMixT: Clone-Specific Genomic Structure Estimation in Cancer
Published in Genome Biology, 2017
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Publications
E-Scape: Interactive Visualization of Single-Cell Phylogenetics and Cancer Evolution
Published in Nature Methods, 2017
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Particle Gibbs Split-Merge Sampling for Bayesian Inference in Mixture Models
Published in Journal of Machine Learning Research, 2017
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ddClone: Joint Statistical Inference of Clonal Populations From Single Cell and Bulk Tumour Sequencing Data
Published in Genome Biology, 2017
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Histological Transformation and Progression in Follicular Lymphoma: A Clonal Evolution Study
Published in PLOS Medicine, 2016
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Divergent Modes of Clonal Spread and Intraperitoneal Mixing in High-Grade Serous Ovarian Cancer
Published in Nature Genetics, 2016
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Clonal Genotype and Population Structure Inference From Single-Cell Tumor Sequencing
Published in Nature Methods, 2016
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Divergent Clonal Selection Dominates Medulloblastoma at Recurrence
Published in Nature, 2016
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Dynamics of Genomic Clones in Breast Cancer Patient Xenografts at Single-Cell Resolution
Published in Nature, 2015
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TITAN: Inference of Copy Number Architectures in Clonal Cell Populations From Tumor Whole-Genome Sequence Data
Published in Genome Research, 2014
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PyClone: Statistical Inference of Clonal Population Structure in Cancer
Published in Nature Methods, 2014
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Distinct Evolutionary Trajectories of Primary High-Grade Serous Ovarian Cancers Revealed Through Spatial Mutational Profiling
Published in Journal of Pathology, 2013
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Mutational and Structural Analysis of Diffuse Large B-Cell Lymphoma Using Whole-Genome Sequencing
Published in Blood, 2013
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Critical Assessment of Automated Flow Cytometry Data Analysis Techniques
Published in Nature Methods, 2013
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Integrative Analysis of Genome-Wide Loss of Heterozygosity and Monoallelic Expression at Nucleotide Resolution Reveals Disrupted Pathways in Triple-Negative Breast Cancer
Published in Genome Research, 2012
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The Clonal and Mutational Evolution Spectrum of Primary Triple-Negative Breast Cancers
Published in Nature, 2012
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JointSNVMix: A Probabilistic Model for Accurate Detection of Somatic Mutations in Normal/Tumour Paired Next-Generation Sequencing Data
Published in Bioinformatics, 2012
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Recurrent Somatic DICER1 Mutations in Nonepithelial Ovarian Cancers
Published in New England Journal of Medicine, 2012
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Feature-Based Classifiers for Somatic Mutation Detection in Tumour-Normal Paired Sequencing Data
Published in Bioinformatics, 2012
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Evolutionary Emergence of N-Glycosylation as a Variable Promoter of HCN Channel Surface Expression
Published in American Journal of Physiology Cell Physiology, 2010
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